Comparative Evaluation of Remineralizing Agents on Early Enamel Lesions in Older Adults

Abstract

This research evaluated and contrasted the efficacy of three distinct remineralizing treatments (Tricalcium phosphate (TCP) paste, Fluoride coating, and Nano-hydroxyapatite gel) with the instrument. The current clinical investigation was conducted on the first 90 carious lesions identified using caries diagnosis guidelines, followed by a baseline recording with the instrument. The chosen initial severe lesions were randomized and categorized into three categories based on treatment methods, with 30 lesions in each category, with the following remineralizing drivers: category A, group B (fluoride varnishes), and category C (nano-hydroxyapatite gels). The remineralizing chemicals were administered for four minutes biweekly for four weeks. During five weeks, the DIAGNO-dent ratings of primary carious lesions were documented to assess the impact of restoring medications. A paired t-test was employed to compare foundation data and follow-up ratings. A one-way Analysis of Variance (ANOVA) was performed to analyze results between all three categories. Post-Hoc Tukey testing was conducted to assess the substantial distinction among every category. Significant variations were seen between the three categories at follow-up (p = 0.001). Within every category, there was an essential difference between baseline and final follow-up grades (p = 0.000 for the three categories). Comparative analyses between each pair of groupings revealed a substantial difference in follow-up records among nano-hydroxyapatite and varnish with fluoride concerning pit and fissure cavities, with nano-hydroxyapatite demonstrating superior efficacy.